The value of serial plasma nuclear and mitochondrial DNA levels in adult community-acquired bacterial meningitis
نویسندگان
چکیده
منابع مشابه
The value of serial plasma nuclear and mitochondrial DNA levels in adult community-acquired bacterial meningitis.
BACKGROUND Increased levels of plasma nuclear and mitochondrial DNA have been reported in critically ill patients. We tested the hypothesis that plasma nuclear and mitochondrial DNA are substantially increased in acute bacterial meningitis and decrease after antimicrobial therapy, and that plasma nuclear and mitochondrial DNA levels can predict treatment outcomes. METHODS We examined serial p...
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BACKGROUND Increased levels of cerebrospinal fluid (CSF) 14-3-3 proteins have been reported in acute bacterial meningitis. We tested the hypothesis that CSF 14-3-3 protein levels are substantially increased in acute bacterial meningitis and decreased after anti-microbial therapy, and that CSF 14-3-3 protein levels can predict treatment outcomes. METHODS We examined serial pan-CSF 14-3-3 (14-3...
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We reviewed the charts of all patients > or = 15 years of age or older in whom community acquired-bacterial meningitis was diagnosed at Srinagarind Hospital, Khon Kaen, Thailand from 1984 through 1998. Eighty-five patients were included in this study. The clinical manifestation was acute meningitis with CSF neutrophilic pleocytosis and low glucose content. Gram's staining of CSF was positive in...
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BACKGROUND Alcoholism is associated with susceptibility to infectious disease, particularly bacterial pneumonia. In the present study we described characteristics in alcoholic patients with bacterial meningitis and delineate the differences with findings in non-alcoholic adults with bacterial meningitis. METHODS/PRINCIPAL FINDINGS This was a prospective nationwide observational cohort study i...
متن کاملDilemmas in the diagnosis of acute community-acquired bacterial meningitis.
Rapid diagnosis and treatment of acute community-acquired bacterial meningitis reduces mortality and neurological sequelae, but can be delayed by atypical presentation, assessment of lumbar puncture safety, and poor sensitivity of standard diagnostic microbiology. Thus, diagnostic dilemmas are common in patients with suspected acute community-acquired bacterial meningitis. History and physical ...
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ژورنال
عنوان ژورنال: QJM
سال: 2010
ISSN: 1460-2725,1460-2393
DOI: 10.1093/qjmed/hcp201